Effect of genipin on the biliary excretion of cholephilic compounds in rats
M Mikami, H Takikawa - Hepatology Research, 2008 - Wiley Online Library
Aim: Genipin, a metabolite of geniposide, is reported to stimulate the insertion of multidrug
resistance protein 2 (Mrp2) in the bile canalicular membrane, and to cause choleresis by
increasing the biliary excretion of glutathione, which has been considered to be a substrate
of Mrp2. In the present study, the effect of colchicine on the choleretic effect of genipin was
investigated. The effect of genipin on the biliary excretion of the substrates of bile salt export
pump and Mrp2 was also studied. Methods: After bile duct cannulation into rats, genipin was …
resistance protein 2 (Mrp2) in the bile canalicular membrane, and to cause choleresis by
increasing the biliary excretion of glutathione, which has been considered to be a substrate
of Mrp2. In the present study, the effect of colchicine on the choleretic effect of genipin was
investigated. The effect of genipin on the biliary excretion of the substrates of bile salt export
pump and Mrp2 was also studied. Methods: After bile duct cannulation into rats, genipin was …
[引用][C] Effect of genipin on the biliary excretion of cholephilic compounds in rats
三神昌樹 - 2008 - ci.nii.ac.jp
CiNii 博士論文 - Effect of genipin on the biliary excretion of cholephilic compounds in rats …
Effect of genipin on the biliary excretion of cholephilic compounds in rats ラットにおける肝
指向性物質の胆汁中排泄におよぼすgenipinの影響 … ラットにおける肝指向性物質の胆汁中排泄
におよぼすgenipinの影響 …
Effect of genipin on the biliary excretion of cholephilic compounds in rats ラットにおける肝
指向性物質の胆汁中排泄におよぼすgenipinの影響 … ラットにおける肝指向性物質の胆汁中排泄
におよぼすgenipinの影響 …
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